Does the 2021 Chevrolet Express need premium gas?

No. Regular.

$0extra a year

Miles a yearGas, $ a gallonPremium gap, $ a gallon

12,000 miles a year. Gas $3.20. Premium $0.60 more.

288 models (2021). One trim per model: the cheapest with a grade.

2021 Chevrolet Express: fuel grade by trim
Trim	Engine	Grade	Mpg	Regular, a year	Premium, a year
Commercial Cutaway 3500 Van 139" RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
Cargo Van RWD 2500 135"	4.3L 6cyl	Regular	N/A	N/A	N/A
Cargo Van RWD 2500 155"	4.3L 6cyl	Regular	N/A	N/A	N/A
Cargo Van RWD 3500 135"	4.3L 6cyl	Regular	N/A	N/A	N/A
Cargo Van RWD 3500 155"	4.3L 6cyl	Regular	N/A	N/A	N/A
2500 Passenger LS RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
2500 Passenger LT RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
3500 Passenger LS RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
3500 Passenger LT RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
Passenger RWD 3500 155" LS	4.3L 6cyl	Regular	N/A	N/A	N/A
Passenger RWD 3500 155" LT	4.3L 6cyl	Regular	N/A	N/A	N/A
2500 Cargo Extended RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
2500 Cargo Regular RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
3500 Cargo Extended RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
3500 Cargo Regular RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
3500 Passenger LS Extended RWD	4.3L 6cyl	Regular	N/A	N/A	N/A
3500 Passenger LT Extended RWD	4.3L 6cyl	Regular	N/A	N/A	N/A

What this cannot tell you

Check the fuel door or manual before you fill.

Gas prices and the premium gap change by state.