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Does the 2020 Mercedes-Benz E-Class need premium gas?

Yes. Premium.

$277extra a year

Pick another car

12,000 miles a year. Gas $3.20. Premium $0.60 more.

Convertibles100%Coupes93%Sedans52%SUVs47%Hatchbacks31%Trucks8%Minivans0%
307 models (2020). One trim per model: the cheapest with a grade.
2020 Mercedes-Benz E-Class: fuel grade by trim
TrimEngineGradeMpgRegular, a yearPremium, a year
E 350 RWD2.0L 4cylPremium26$1,477$1,754
E 350 4MATIC AWD2.0L 4cylPremium26$1,477$1,754
E 450 4MATIC AWD3.0L 6cylPremium23$1,670$1,983
E 450 RWD3.0L 6cylPremium23$1,670$1,983
E 450 4MATIC AWD3.0L 6cylPremium22$1,745$2,073
E 450 4MATIC AWD3.0L 6cylPremium22$1,745$2,073
E 450 RWD Cabriolet3.0L 6cylPremium23$1,670$1,983
E 450 4MATIC Cabriolet AWD3.0L 6cylPremium22$1,745$2,073

Rivals

2020 Mercedes-Benz E-Class and rivals: grade of the cheapest trim
CarCheapest trimGrade
2020 Mercedes-Benz E-ClassE 350 RWDPremium
2020 BMW 5 Series530i RWDPremium
2020 Acura RLXFWDPremium
2020 Audi A645 TFSI Premium AWDPremium
2020 Audi RS 3AWDPremium
2020 Jaguar XF25t Premium RWDPremium
2020 Lexus GS350 AWDPremium

What this cannot tell you

Check the fuel door or manual before you fill.

Gas prices and the premium gap change by state.

How values are checked