2025 Mercedes-Benz S-Class mpg
Combined mpg, S 500 4MATIC AWD
24mpg
- 21 city, 31 highway.
- 2 mpg below the median of 68 sedans (2025).
- 8 trims: 15 to 24 mpg.
12,000 miles a year. Gas $3.20. Power 17 cents per kWh. Plug-in trims: 50% electric miles.
| Trim | Engine | Drive | City mpg | Hwy mpg | Combined | Tank, gal | Miles per tank | Cost a year |
|---|---|---|---|---|---|---|---|---|
| S 500 4MATIC AWD | 3.0L 6cyl | AWD | 21 | 31 | 24 | 20.0 | 480 | $1,600 |
| S 580e 4MATIC AWD | 3.0L 6cyl | AWD | 12 | 20 | 23 | 17.7 | 407 | $1,386 |
| S 580 4MATIC AWD | 4.0L 8cyl | AWD | 17 | 27 | 20 | 20.0 | 400 | $1,920 |
| Maybach S 580 4MATIC | 4.0L | AWD | 16 | 27 | 20 | N/A | N/A | $1,920 |
| AMG S 63 E 4MATIC Sedan | 4.0L | AWD | 12 | 20 | 18 | N/A | N/A | $2,133 |
| AMG S 63 E Performance 4MATIC | N/A | AWD | 12 | 20 | 15 | N/A | N/A | $2,560 |
| Maybach S 680 4MATIC | 6.0L | AWD | 12 | 20 | 15 | N/A | N/A | $2,560 |
| Mercedes-AMG S-Class S 63 E Performance 4MATIC+ AWD | 4.0L 8cyl | AWD | 12 | 20 | 15 | 20.0 | 300 | $2,560 |
Plug-in trims: 50% electric miles.
Fuel cost
S 500 4MATIC AWD, 24 mpg combined.
- Per year
- $1,600
- Per month
- $133
- Per mile
- 13.3 cents
- Fill the tank
- $64.00
- Top trim: Maybach S 680 4MATIC. $2,560 a year. $960 more than the S 500 4MATIC AWD.
Plug-in hybrid trims
| Trim | Electric range, mi | MPGe | kWh per 100 mi | Gas mpg | Cost a year |
|---|---|---|---|---|---|
| S 580e 4MATIC AWD | 48 | 63 | 54.0 | 23 | $1,386 |
Cost a year: 50% electric miles, the rest on gas.
Trip cost
| Trip | Gallons | Cost |
|---|---|---|
| 100 miles | 3.2 | $10.32 |
| 300 miles | 9.7 | $30.97 |
| 500 miles | 16.1 | $51.61 |
| 1,000 miles | 32.3 | $103 |
Commute cost
- Per month
- $116
- Per year
- $1,387
- Miles a month
- 867
S 500 4MATIC AWD. 20 miles each way, 5 days a week.
Is 24 mpg good? Yes. Beats 52% of 2026 cars.
MPG by year
Rivals
| Car | Cheapest trim | MPG or range | Compare |
|---|---|---|---|
| 2025 Mercedes-Benz S-Class | S 500 4MATIC AWD | 24 mpg | |
| 2025 BMW M5 | AWD | 14 mpg | Compare |
| 2025 Audi S8 | 4.0 TFSI AWD | 18 mpg | Compare |
| 2025 Audi e-tron GT | Premium Plus AWD | 85 MPGe | |
| 2025 Audi S e-tron GT | Premium Plus AWD | 300 mi range | Compare |
| 2025 Audi RS 7 | performance AWD | 17 mpg | Compare |
What this cannot tell you
EPA ratings. Your own mpg will differ.
Gas prices change by state and by week.
- 2 or more sources
- 1 source
- Model-level, rule or estimate
- Sources disagree