2021 Mercedes-Benz E-Class mpg
Combined mpg, E 350 RWD
25mpg
- 22 city, 31 highway.
- 1 mpg below the median of 81 sedans (2021).
- 15 trims: 18 to 26 mpg.
12,000 miles a year. Gas $3.20.
| Trim | Engine | Drive | City mpg | Hwy mpg | Combined | Tank, gal | Miles per tank | Cost a year |
|---|---|---|---|---|---|---|---|---|
| E 450 4MATIC AWD | 3.0L 6cyl | AWD | 23 | 30 | 26 | 21.1 | 549 | $1,477 |
| E 450 RWD | 3.0L 6cyl | RWD | 23 | 31 | 26 | 17.4 | 452 | $1,477 |
| E 350 RWD | N/A | RWD | 22 | 31 | 25 | N/A | N/A | $1,536 |
| E 350 RWD | 2.0L 4cyl | RWD | 22 | 31 | 25 | 17.4 | 435 | $1,536 |
| E 350 4MATIC AWD | 2.0L 4cyl | AWD | 22 | 30 | 25 | 17.4 | 435 | $1,536 |
| E 450 4MATIC AWD | 3.0L 6cyl | AWD | 23 | 30 | 25 | 17.4 | 435 | $1,536 |
| E 450 RWD Cabriolet | 3.0L 6cyl | RWD | 23 | 30 | 25 | 17.4 | 435 | $1,536 |
| AMG 53 E Sedan 4MATIC | 3.0L | AWD | 22 | 29 | 25 | N/A | N/A | $1,536 |
| E 450 4MATIC Cabriolet AWD | 3.0L 6cyl | AWD | 23 | 29 | 25 | 17.4 | 435 | $1,536 |
| E 450 4MATIC All-Terrain Wagon | 3.0L | AWD | 22 | 28 | 24 | N/A | N/A | $1,600 |
| E 450 4MATIC AWD | 3.0L 6cyl | AWD | 22 | 28 | 24 | N/A | N/A | $1,600 |
| AMG E 53 Coupe 4MATIC | 3.0L | AWD | 21 | 28 | 24 | N/A | N/A | $1,600 |
| AMG E 53 Cabriolet 4MATIC | 3.0L | AWD | 21 | 27 | 23 | N/A | N/A | $1,670 |
| AMG E 63 S Sedan 4MATIC | 4.0L | AWD | 16 | 23 | 18 | N/A | N/A | $2,133 |
| AMG E 63 S Wagon 4MATIC | 4.0L | AWD | 16 | 23 | 18 | N/A | N/A | $2,133 |
Fuel cost
E 350 RWD, 25 mpg combined.
- Per year
- $1,536
- Per month
- $128
- Per mile
- 12.8 cents
- Best mpg: E 450 4MATIC AWD, 26 mpg. $1,477 a year.
- Top trim: AMG E 63 S Wagon 4MATIC. $2,133 a year. $597 more than the E 350 RWD.
Trip cost
| Trip | Gallons | Cost |
|---|---|---|
| 100 miles | 3.2 | $10.32 |
| 300 miles | 9.7 | $30.97 |
| 500 miles | 16.1 | $51.61 |
| 1,000 miles | 32.3 | $103 |
Commute cost
- Per month
- $111
- Per year
- $1,331
- Miles a month
- 867
E 350 RWD. 20 miles each way, 5 days a week.
Is 25 mpg good? Yes. Beats 58% of 2026 cars.
MPG by year
Rivals
| Car | Cheapest trim | Combined mpg | Compare |
|---|---|---|---|
| 2021 Mercedes-Benz E-Class | E 350 RWD | 25 mpg | |
| 2021 BMW 5 Series | 530i RWD | 28 mpg | |
| 2021 Audi A6 | 45 TFSI Premium AWD | 26 mpg | Compare |
| 2021 Volvo S90 | T6 Momentum AWD | 25 mpg | |
| 2021 Audi S4 | Premium AWD | 23 mpg |
What this cannot tell you
EPA ratings. Your own mpg will differ.
Gas prices change by state and by week.
- 2 or more sources
- 1 source
- Model-level, rule or estimate
- Sources disagree